Weight Loss

Semaglutide: A Promising Weight Loss Drug

Semaglutide is a breakthrough treatment for people who struggle with serious, chronic weight management challenges. First isolated as an effective diabetes drug, this insulin-boosting medication is now available to patients who need to lose a significant amount of weight in a consistent way and achieve results long-term. This treatment method doesn’t rely on stimulants, harmful crash diets, unsustainable exercise plans, or any other mechanism that can jeopardize the patient’s overall health.

What Is Semaglutide?

Unless you’re a healthcare professional or have Type 2 diabetes, it’s entirely possible that you’ve never heard of semaglutide before. Despite its relatively new application as a powerful weight loss drug, semaglutide is actually an extremely safe and well-researched substance. It has already been prescribed for several years and used by diabetes patients as an injectable medicine used for the management of diabetes by improving glycemic control.

In recent months, this medication has been taking the world of weight loss by storm. The FDA (United States Food and Drug Administration) recently approved semaglutide as a prescription weight loss aid. Its approval has already improved the lives of many chronically overweight patients by assisting in safe and consistent weight loss.

There’s no need to struggle with perpetual cycles of weight loss and gain. There’s also no need to live with the hopeless feeling that comes with an inability to manage serious weight issues with diet and exercise alone. Hundreds of millions of people worldwide turn to modern medicine every day to keep their bodies in the best possible condition. It’s long past time to end the stigma associated with seeking medical intervention for serious weight management issues.

Your dedication to healthy lifestyle choices will be crucial for sustainable, long-term weight management. However, injectable semaglutide treatment is an extremely valuable tool. It can help you achieve your goal of having better overall health by getting you on track towards a healthy weight. With weekly semaglutide injections, you can reach your ideal body weight in a way that can be maintained for the rest of your life. You can do so without turning to starvation-based “diets” or unrealistic 30-day workout programs.

Semaglutide for Weight Loss

Semaglutide is a GLP-1 (glucagon-like-peptide-1) receptor agonist. It has emerged as a life-changing option for overweight or obese people who are committed to shedding a significant amount of weight and do not have other significant underlying health issues. Semaglutide is not a miracle cure or a gimmicky “fat-burning” supplement. It is a long-acting prescription medicine designed to be used over an extended period of several months or more.

Semaglutide injections are not an appropriate treatment for people who only need to lose a small amount of weight or have a body mass index (BMI) of 27 or less. It is also not appropriate for those who are looking for an “instant” or short-term weight loss fix.

Does Semaglutide Really Work for Losing Weight?

There is an impressive body of scientific evidence backing semaglutide’s effectiveness as a weight-loss drug. Some of the research that was conducted leading up to its recent FDA approval for weight management includes:

A randomized, double-blind trial occurring over a long period in the mid-2010s found that semaglutide use resulted in significant body weight reductions. This weight reduction was not only compared to a placebo group, but also compared to another substance in the GLP-1 receptor agonist class called Liraglutide.[1]

A 2019 report found that semaglutide “appears to be superior” for weight loss stimulation in type 2 diabetes patients when evaluated compared to a variety of other GLP-1 receptor agonists. The same study noted that trials evaluating semaglutide as a weight-loss drug exceeded the criterion set forth by both the FDA and EMA (European Medicines Agency) for obesity medications. This was regardless of whether the patients evaluated were Type 2 diabetics, and that it achieved these results with “no safety concerns”.[2]

A more recent double-blind trial involved nearly 2,000 individuals who were not diagnosed with diabetes and had a BMI over 30. When individuals implemented other lifestyle changes such as exercise, this study found the mean change in body weight after 68 weeks of semaglutide treatment was -14.9%. The placebo group only saw a -2.4% change.[3]

Another interesting study from 2020 concluded that semaglutide provides superior weight loss efficacy with no demonstrable link to “gastrointestinal adverse events.” Gastrointestinal adverse events included negative side effects in the stomach and digestive system, such as stomachaches and diarrhea.[4]

Yet another study focusing on semaglutide and weight loss paired the substance (or, alternately, a placebo) with intensive behavioral therapy and a low-calorie diet. This study also concluded that semaglutide use resulted in demonstrably superior weight loss outcomes.[5]

How Does Semaglutide Work?

Semaglutide is in a class of medications called glucagon-like peptide 1 (GLP-1) agonists. GLP-1 agonists work by stimulating your pancreas to increase insulin. This additional insulin causes the stomach to empty over a longer period of time. The idea of the stomach processing food more slowly can seem counterintuitive to patients who have turned to stimulant-based diet pills in the past. However, this slow and consistent digestion is merely an early step in the chain reaction that makes semaglutide such an effective weight loss drug.

When your stomach takes more time to empty itself of food, it sends signals of “fullness” to the brain. This signal is sent throughout a larger portion of your day, even if you’re eating less food than usual. The end result of this process is a powerful appetite suppression effect based on the patient’s own natural insulin production. This means patients can benefit from medically assisted weight loss without any need for invasive surgeries or harsh stimulants.

A semaglutide regimen will also lead to healthier blood sugar levels, which can help you feel more energetic throughout your day. Stabilized and controlled blood sugar levels can also help improve other areas of your overall health. Even if you aren’t at risk for diabetes, this effect can contribute to a general sense of well-being, which is a crucial component in any weight loss journey.

Tirzepatide Plus

Tirzepatide Plus is a once-weekly GIP (glucose-dependent insulinotropic polypeptide) receptor and GLP-1 (glucagon-like peptide-1) receptor agonist, representing a new class of medicines studied for the treatment of obesity. Tirzepatide is a single peptide that triggers the body’s receptors for GIP and GLP-1, two natural incretin hormones. Cyanocobalamin will help increase energy.

GIP has decreased food intake and increased energy expenditure, resulting in weight reductions. Combined with a GLP-1 receptor agonist, it has a more significant effect on glucose and body weight effects.

• Substantial A1C reductions.
• Boosted weight loss.
• Improvements in cardiometabolic measures.
• Reduce appetite.